AMD updates Instinct data center GPU line

In 2025, AMD plans to release the new AMD CDNA 4 architecture and with it the Instinct MI350 series, which AMD says will bring up to a 35x increase in AI inference performance compared to AMD Instinct MI300 Series. And in 2026, the AMD Instinct MI400 series will arrive, based on the AMD CDNA “Next” architecture.

“With our updated annual cadence of products, we are relentless in our pace of innovation, providing the leadership capabilities and performance the AI industry and our customers expect to drive the next evolution of data center AI training and inference,” said Brad McCredie, corporate vice president, data center accelerated compute, AMD, in a statement.

The MI350X will come with 288 GB of HBM3e, like the MI325X. The chip will be manufactured using a 3-nanometer process – a notable shrink in transistor size from 6nm nodes used for MI300 chips – and add support for FP4 and FP6 floating point data formats. The FP6 is new and unique to AMD. Intel and Nvidia have embraced FP4 and FP8 but not 6-bit.